Mouse Bmpr1b activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Bmpr1b
Locus ID	12167
Kit Components	GA200427G1, Bmpr1b gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA200427G2, Bmpr1b gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA200427G3, Bmpr1b gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001277216, NM_001277217, NM_001277218, NM_001277220, NM_007560
Synonyms	Acvrlk6; AI385617; ALK-6; Alk6; AV355320; BMPR-1B; BMPR-IB; CFK-43a; SKR6
Summary	This gene encodes a serine/threonine kinase that functions as a receptor for bone morphogenetic proteins (BMPs). The encoded protein is a type I receptor, and forms a complex of two type II and two type I receptors at the cell membrane. This complex signals downstream to activate SMAD transcriptional regulators. This signaling is important in skeletal and bone development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2013]

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