Mouse Bcl10 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Bcl10
Locus ID	12042
Kit Components	GA200381G1, Bcl10 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA200381G2, Bcl10 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA200381G3, Bcl10 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_009740
Synonyms	AI132454; BCL-10; C81403; CARMEN; cE10; CIPER; CLAP; ME10
Summary	Involved in adaptive immune response. Promotes apoptosis, pro-caspase-9 maturation and activation of NF-kappa-B via NIK and IKK. May be an adapter protein between upstream TNFR1-TRADD-RIP complex and the downstream NIK-IKK-IKAP complex. Is a substrate for MALT1.[UniProtKB/Swiss-Prot Function]

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