Mouse Asgr1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Asgr1
Locus ID	11889
Kit Components	GA200296G1, Asgr1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA200296G2, Asgr1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA200296G3, Asgr1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001291131, NM_001291132, NM_009714
Synonyms	ASGPR1; Asgr; Asgr-1; HL-1
Summary	Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. The receptor recognizes terminal galactose and N-acetylgalactosamine units. After ligand binding to the receptor, the resulting complex is internalized and transported to a sorting organelle, where receptor and ligand are disassociated. The receptor then returns to the cell membrane surface.[UniProtKB/Swiss-Prot Function]

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