Mouse Rhoa activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Rhoa
Locus ID	11848
Kit Components	GA200272G1, Rhoa gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA200272G2, Rhoa gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA200272G3, Rhoa gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_016802
Synonyms	Arha; Arha1; Arha2
Summary	This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants have been identified. [provided by RefSeq, Sep 2015]

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