Mouse Aqp2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Aqp2
Locus ID	11827
Kit Components	GA200251G1, Aqp2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA200251G2, Aqp2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA200251G3, Aqp2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_009699
Synonyms	AQP-CD; cph; jpk; WCH-CD
Summary	Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient (PubMed:10191086). Plays an essential role in renal water homeostasis (PubMed:16641094).[UniProtKB/Swiss-Prot Function]

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