Mouse Api5 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Api5
Locus ID	11800
Kit Components	GA200232G1, Api5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA200232G2, Api5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA200232G3, Api5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001305258, NM_007466, NM_001349003
Synonyms	AAC-11; AI196452; API-5
Summary	Antiapoptotic factor that may have a role in protein assembly. Negatively regulates ACIN1. By binding to ACIN1, it suppresses ACIN1 cleavage from CASP3 and ACIN1-mediated DNA fragmentation. Also known to efficiently suppress E2F1-induced apoptosis (By similarity).[UniProtKB/Swiss-Prot Function]

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