Mouse Aldh3a1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Aldh3a1
Locus ID	11670
Kit Components	GA200159G1, Aldh3a1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA200159G2, Aldh3a1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA200159G3, Aldh3a1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001112725, NM_001331112, NM_007436
Synonyms	Ahd-4; Ahd4; Aldh; Aldh3
Summary	ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde (Probable). They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation (Probable). Oxidizes medium and long chain aldehydes into non-toxic fatty acids (PubMed:25286108). Preferentially oxidizes aromatic aldehyde substrates (PubMed:11784860). Comprises about 50 percent of corneal epithelial soluble proteins (PubMed:11784860). May play a role in preventing corneal damage caused by ultraviolet light (PubMed:10376761).[UniProtKB/Swiss-Prot Function]

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