Mouse Agtrap activation kit by CRISPRa
CAT#: GA200129
Agtrap CRISPRa kit - CRISPR gene activation of mouse angiotensin II, type I receptor-associated protein
CNY 12,255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | Agtrap |
Locus ID | 11610 |
Kit Components | GA200129G1, Agtrap gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA200129G2, Agtrap gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA200129G3, Agtrap gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_001301281, NM_009642 |
Synonyms | 3300002E14Rik; AT1R; Atrap; D4Wsu124e |
Summary | Appears to be a negative regulator of type-1 angiotensin II receptor-mediated signaling by regulating receptor internalisation as well as mechanism of receptor desensitization such as phosphorylation. Induces also a decrease in angiotensin II-stimulated transcriptional activity. May play a role of negative regulator in cardiomyocyte hypertrophy induced by angiotensin II through an inhibition of p38 mitogen-activated protein kinase pathway.[UniProtKB/Swiss-Prot Function] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN501002 | Agtrap - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |