Mouse Acvr1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Acvr1
Locus ID	11477
Kit Components	GA200052G1, Acvr1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA200052G2, Acvr1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA200052G3, Acvr1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001110204, NM_001110205, NM_007394, NM_001355048, NM_001355049
Synonyms	ActR-I; ActRIA; Acvr; Acvrlk2; Alk-2; ALK2; Alk8; D330013D15Rik; SKR1; Tsk7L
Summary	On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin. May be involved in left-right pattern formation during embryogenesis.[UniProtKB/Swiss-Prot Function]

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