Mouse Acvr1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Acvr1
Locus ID	11477
Kit Components	GA200052G1, Acvr1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA200052G2, Acvr1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA200052G3, Acvr1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001110204, NM_001110205, NM_007394, NM_001355048, NM_001355049
Synonyms	ActR-I; ActRIA; Acvr; Acvrlk2; Alk-2; ALK2; Alk8; D330013D15Rik; SKR1; Tsk7L
Summary	On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin. May be involved in left-right pattern formation during embryogenesis.[UniProtKB/Swiss-Prot Function]

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