Human GIMAP6 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	GIMAP6
Locus ID	474344
Kit Components	GA118568G1, GIMAP6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA118568G2, GIMAP6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA118568G3, GIMAP6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001007224, NM_001244071, NM_001244072, NM_024711, NR_024115
Synonyms	DKFZp686A01175; FLJ22690; GTPase, IMAP family member 6; hIAN2; human immune associated nucleotide 2; IAN6; IAN6, hIAN2, FLJ22690, DKFZp686A01175; immune associated nucleotide 2; immune associated nucleotide 6
Summary	This gene encodes a member of the GTPases of immunity-associated proteins (GIMAP) family. GIMAP proteins contain GTP-binding and coiled-coil motifs, and may play roles in the regulation of cell survival. Decreased expression of this gene may play a role in non-small cell lung cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, which is found in a cluster with seven additional GIMAP genes on the long arm of chromosome 7. [provided by RefSeq, Sep 2011]

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