Human KCNT2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	KCNT2
Locus ID	343450
Kit Components	GA117573G1, KCNT2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA117573G2, KCNT2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA117573G3, KCNT2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001287819, NM_001287820, NM_198503, NR_146057, NR_146058
Synonyms	KCa4.2; SLICK; SLO2.1
Summary	Outward rectifying potassium channel. Produces rapidly activating outward rectifier K(+) currents. Activated by high intracellular sodium and chloride levels (PubMed:14684870, PubMed:16687497, PubMed:29069600). Channel activity is inhibited by ATP and by inhalation anesthetics, such as isoflurane (PubMed:16687497) (By similarity). Inhibited upon stimulation of G-protein coupled receptors, such as CHRM1 and GRM1 (PubMed:16687497).[UniProtKB/Swiss-Prot Function]

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