Human ALKBH3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ALKBH3
Locus ID	221120
Kit Components	GA116594G1, ALKBH3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA116594G2, ALKBH3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA116594G3, ALKBH3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_139178
Synonyms	ABH3; DEPC-1; DEPC1; PCA1
Summary	The Escherichia coli AlkB protein protects against the cytotoxicity of methylating agents by repair of the specific DNA lesions generated in single-stranded DNA. ALKBH2 (MIM 610602) and ALKBH3 are E. coli AlkB homologs that catalyze the removal of 1-methyladenine and 3-methylcytosine (Duncan et al., 2002 [PubMed 12486230]).[supplied by OMIM, Mar 2008]

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