Human LRTOMT activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	LRTOMT
Locus ID	220074
Kit Components	GA116559G1, LRTOMT gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA116559G2, LRTOMT gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA116559G3, LRTOMT gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001145307, NM_001145308, NM_001145309, NM_001145310, NM_001205138, NM_001271471, NM_145309, NR_026886, NR_134858, NR_073187, NR_073188
Synonyms	CFAP111; DFNB63; LRRC51
Summary	This locus represents naturally occurring readthrough transcription between the neighboring LRRC51 (leucine-rich repeat containing 51) and TOMT (transmembrane O-methyltransferase) genes on chromosome 11. The readthrough transcript encodes a fusion protein that shares sequence identity with each individual gene product. Multiple reports implicate mutations in this gene in nonsyndromic deafness.[provided by RefSeq, Feb 2021]

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