Human C1orf86 (FAAP20) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	FAAP20
Locus ID	199990
Kit Components	GA116327G1, C1orf86 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA116327G2, C1orf86 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA116327G3, C1orf86 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001146310, NM_001256945, NM_001256946, NM_001256947, NM_001282670, NM_001282671, NM_001282672, NM_001282673, NM_182533, NR_046424, NR_046425, NR_046426, NR_046427
Synonyms	C1orf86; FP7162
Summary	Component of the Fanconi anemia (FA) complex required to recruit the FA complex to DNA interstrand cross-links (ICLs) and promote ICLs repair. Following DNA damage recognizes and binds 'Lys-63'-linked ubiquitin generated by RNF8 at ICLs and recruits other components of the FA complex. Promotes translesion synthesis via interaction with REV1.[UniProtKB/Swiss-Prot Function]

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