Human UBR1 activation kit by CRISPRa

CAT#: GA116293

UBR1 CRISPRa kit - CRISPR gene activation of human ubiquitin protein ligase E3 component n-recognin 1



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (2)
Rabbit Polyclonal Anti-UBR1 Antibody
    • 100 ul

CNY 5,250.00


UBR1 (Myc-DDK-tagged)-Human ubiquitin protein ligase E3 component n-recognin 1 (UBR1)
    • 10 ug

CNY 17,632.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol UBR1
Locus ID 197131
Kit Components

GA116293G1, UBR1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA116293G2, UBR1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA116293G3, UBR1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_174916
Synonyms JBS
Summary The N-end rule pathway is one proteolytic pathway of the ubiquitin system. The recognition component of this pathway, encoded by this gene, binds to a destabilizing N-terminal residue of a substrate protein and participates in the formation of a substrate-linked multiubiquitin chain. This leads to the eventual degradation of the substrate protein. The protein described in this record has a RING-type zinc finger and a UBR-type zinc finger. Mutations in this gene have been associated with Johanson-Blizzard syndrome. [provided by RefSeq, Jul 2008]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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