Human Desmoglein 4 (DSG4) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	DSG4
Locus ID	147409
Kit Components	GA115608G1, Desmoglein 4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA115608G2, Desmoglein 4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA115608G3, Desmoglein 4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001134453, NM_177986
Synonyms	CDGF13; CDHF13; HYPT6; LAH
Summary	This gene encodes a member of the desmoglein subgroup of desmosomal cadherins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein is a transmembrane component of desmosomes and may play a role in cell-cell adhesion in epithelial cells. Mutations in the gene are associated with localized autosomal recessive hypotrichosis and monilethrix, characterized by impaired hair growth. [provided by RefSeq, May 2016]

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