Human PLEKHA7 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PLEKHA7
Locus ID	144100
Kit Components	GA115478G1, PLEKHA7 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA115478G2, PLEKHA7 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA115478G3, PLEKHA7 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_175058, NM_001329630, NM_001329631
Synonyms	DKFZp686M22243
Summary	Required for zonula adherens biogenesis and maintenance. Acts via its interaction with KIAA1543/Nezha, which anchors microtubules at their minus-ends to zonula adherens, leading to the recruitment of KIFC3 kinesin to the junctional site.[UniProtKB/Swiss-Prot Function]

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