Human FGFBP3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	FGFBP3
Locus ID	143282
Kit Components	GA115454G1, FGFBP3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA115454G2, FGFBP3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA115454G3, FGFBP3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_152429
Synonyms	C10orf13; FGF-BP3
Summary	Heparin-binding protein which binds to FGF2, prevents binding of FGF2 to heparin and probably inhibits immobilization of FGF2 on extracellular matrix glycosaminoglycans, allowing its release and subsequent activation of FGFR signaling which leads to increased vascular permeability.[UniProtKB/Swiss-Prot Function]

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