Human ZFYVE27 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ZFYVE27
Locus ID	118813
Kit Components	GA114674G1, ZFYVE27 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA114674G2, ZFYVE27 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA114674G3, ZFYVE27 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001002261, NM_001002262, NM_001174119, NM_001174120, NM_001174121, NM_001174122, NM_144588
Synonyms	PROTRUDIN; SPG33
Summary	This gene encodes a protein with several transmembrane domains, a Rab11-binding domain and a lipid-binding FYVE finger domain. The encoded protein appears to promote neurite formation. A mutation in this gene has been reported to be associated with hereditary spastic paraplegia, however the pathogenicity of the mutation, which may simply represent a polymorphism, is unclear. [provided by RefSeq, Mar 2010]

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