Human CACNA2D4 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	CACNA2D4
Locus ID	93589
Kit Components	GA114291G1, CACNA2D4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA114291G2, CACNA2D4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA114291G3, CACNA2D4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001005737, NM_001005766, NM_172364
Synonyms	calcium channel, voltage-dependent, alpha 2/delta subunit 4; RCD4; voltage-gated calcium channel alpha(2)delta-4 subunit
Summary	This gene encodes a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008]

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