Human Dermokine (DMKN) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	DMKN
Locus ID	93099
Kit Components	GA114262G1, Dermokine gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA114262G2, Dermokine gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA114262G3, Dermokine gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001035516, NM_001126056, NM_001126057, NM_001126058, NM_001126059, NM_001126061, NM_001190347, NM_001190348, NM_001190349, NM_001308380, NM_001308383, NM_033317, NR_033746, NM_001352328, NM_001352329, NM_001352330, NM_001352331, NM_001352332, NR_147958, NR_147959
Synonyms	UNQ729; ZD52F10
Summary	This gene is upregulated in inflammatory diseases, and it was first observed as expressed in the differentiated layers of skin. The most interesting aspect of this gene is the differential use of promoters and terminators to generate isoforms with unique cellular distributions and domain components. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jun 2010]

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