Human Membralin (TMEM259) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	TMEM259
Locus ID	91304
Kit Components	GA114102G1, Membralin gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA114102G2, Membralin gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA114102G3, Membralin gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001033026, NM_033420
Synonyms	ASBABP1; C19orf6; MBRL; MEMBRALIN; R32184_3
Summary	May have a role in the ERAD pathway required for clearance of misfolded proteins in the endoplasmic reticulum (ER). Promotes survival of motor neurons, probably by protecting against ER stress.[UniProtKB/Swiss-Prot Function]

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