Human ZIC5 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ZIC5
Locus ID	85416
Kit Components	GA113877G1, ZIC5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA113877G2, ZIC5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA113877G3, ZIC5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_033132, NR_146224, NR_146225
Synonyms	OTTHUMP00000040732; Zic family member 5 (odd-paired homolog, Drosophila); zinc family member 5 protein; zinc finger protein of the cerebellum 5
Summary	This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. The encoded protein may act as a transcriptional repressor. Studies in mouse and Xenopus support a role for this gene in neural crest development. Elevated expression of this gene has been observed in various human cancers and may contribute to cancer progression. This gene is closely linked to a related family member on chromosome 13. [provided by RefSeq, Mar 2017]

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