Human USP45 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	USP45
Locus ID	85015
Kit Components	GA113829G1, USP45 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA113829G2, USP45 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA113829G3, USP45 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001080481, NM_001346021, NM_001346022, NM_001346023, NM_001346024, NM_001346025, NM_001346026, NM_001346027, NM_001346028, NM_001346029, NM_001346030, NM_001346033, NM_032929, NR_144344, NR_144345, NR_144346, NR_144347, NR_144348
Synonyms	MGC14793
Summary	The protein encoded by this gene is a deubiquitylase that binds ERCC1, the catalytic subunit of the XPF-ERCC1 DNA repair endonuclease. This endonuclease is a critical regulator of DNA repair processes, and the deubiquitylase activity of the encoded protein is important for maintaining the DNA repair ability of XPF-ERCC1. [provided by RefSeq, Sep 2016]

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