Human BCL2L12 activation kit by CRISPRa
CAT#: GA113209
BCL2L12 CRISPRa kit - CRISPR gene activation of human BCL2 like 12
CNY 12,255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | BCL2L12 |
Locus ID | 83596 |
Kit Components | GA113209G1, BCL2L12 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA113209G2, BCL2L12 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA113209G3, BCL2L12 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_001040668, NM_001282516, NM_001282517, NM_001282519, NM_001282520, NM_001282521, NM_052842, NM_138639, NR_104200, NR_104201, NR_104202, NR_104203, NR_104204, NR_104205 |
Synonyms | MGC120313; MGC120314; MGC120315 |
Summary | This gene encodes a member of a family of proteins containing a Bcl-2 homology domain 2 (BH2). The encoded protein is an anti-apoptotic factor that acts as an inhibitor of caspases 3 and 7 in the cytoplasm. In the nucleus, it binds to the p53 tumor suppressor protein, preventing its association with target genes. Overexpression of this gene has been detected in a number of different cancers. There is a pseudogene for this gene on chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN414730 | BCL2L12 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |
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