Human BCL2L12 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	BCL2L12
Locus ID	83596
Kit Components	GA113209G1, BCL2L12 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA113209G2, BCL2L12 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA113209G3, BCL2L12 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001040668, NM_001282516, NM_001282517, NM_001282519, NM_001282520, NM_001282521, NM_052842, NM_138639, NR_104200, NR_104201, NR_104202, NR_104203, NR_104204, NR_104205
Synonyms	MGC120313; MGC120314; MGC120315
Summary	This gene encodes a member of a family of proteins containing a Bcl-2 homology domain 2 (BH2). The encoded protein is an anti-apoptotic factor that acts as an inhibitor of caspases 3 and 7 in the cytoplasm. In the nucleus, it binds to the p53 tumor suppressor protein, preventing its association with target genes. Overexpression of this gene has been detected in a number of different cancers. There is a pseudogene for this gene on chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

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