Human NPL activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	NPL
Locus ID	80896
Kit Components	GA113008G1, NPL gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA113008G2, NPL gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA113008G3, NPL gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001200050, NM_001200051, NM_001200052, NM_001200056, NM_030769
Synonyms	C1orf13; C112; NAL; NPL1
Summary	This gene encodes a member of the N-acetylneuraminate lyase sub-family of (beta/alpha)(8)-barrel enzymes. N-acetylneuraminate lyases regulate cellular concentrations of N-acetyl-neuraminic acid (sialic acid) by mediating the reversible conversion of sialic acid into N-acetylmannosamine and pyruvate. A pseudogene of this gene is located on the short arm of chromosome 2. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]

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