Human HSD3B7 activation kit by CRISPRa
CAT#: GA112898
HSD3B7 CRISPRa kit - CRISPR gene activation of human hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
CNY 12,255.00
CNY 3,656.00
CNY 3,990.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | HSD3B7 |
Locus ID | 80270 |
Kit Components | GA112898G1, HSD3B7 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA112898G2, HSD3B7 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA112898G3, HSD3B7 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_001142777, NM_001142778, NM_025193 |
Synonyms | CBAS1; PFIC4; SDR11E3 |
Summary | This gene encodes an enzyme which is involved in the initial stages of the synthesis of bile acids from cholesterol and a member of the short-chain dehydrogenase/reductase superfamily. The encoded protein is a membrane-associated endoplasmic reticulum protein which is active against 7-alpha hydrosylated sterol substrates. Mutations in this gene are associated with a congenital bile acid synthesis defect which leads to neonatal cholestasis, a form of progressive liver disease. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN402468 | HSD3B7 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |