Human DOK3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	DOK3
Locus ID	79930
Kit Components	GA112737G1, DOK3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA112737G2, DOK3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA112737G3, DOK3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001144875, NM_001144876, NM_001308235, NM_001308236, NM_024872
Synonyms	DOKL
Summary	DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK3 is a negative regulator of JNK signaling in B-cells through interaction with INPP5D/SHIP1. May modulate ABL1 function (By similarity).[UniProtKB/Swiss-Prot Function]

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