Human ALS2CR8 (CARF) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	CARF
Locus ID	79800
Kit Components	GA112635G1, ALS2CR8 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA112635G2, ALS2CR8 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA112635G3, ALS2CR8 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001104586, NM_001282910, NM_001282911, NM_001282912, NM_001322427, NM_001322428, NM_001322429, NM_001322430, NM_024744, NR_136330, NR_136331, NM_001352676, NM_001352677, NM_001352678, NM_001352679, NR_148033, NR_148034
Synonyms	ALS2CR8; NYD-SP24
Summary	Acts as a transcriptional activator that mediates the calcium- and neuron-selective induction of BDNF exon III transcription. Binds to the consensus calcium-response element CaRE1 5'-CTATTTCGAG-3' sequence.[UniProtKB/Swiss-Prot Function]

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