Human B7H4 (VTCN1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	VTCN1
Locus ID	79679
Kit Components	GA112543G1, B7H4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA112543G2, B7H4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA112543G3, B7H4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001253849, NM_001253850, NM_024626, NR_045603, NR_045604
Synonyms	B7-H4; B7h.5; B7H4; B7S1; B7X; PRO1291; VCTN1
Summary	This gene encodes a protein belonging to the B7 costimulatory protein family. Proteins in this family are present on the surface of antigen-presenting cells and interact with ligand bound to receptors on the surface of T cells. Studies have shown that high levels of the encoded protein has been correlated with tumor progression. A pseudogene of this gene is located on chromosome 20. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]

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