Human FAT4 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	FAT4
Locus ID	79633
Kit Components	GA112505G1, FAT4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA112505G2, FAT4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA112505G3, FAT4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001291285, NM_001291303, NM_024582
Synonyms	CDHF14; CDHR11; FAT-J; FATJ; HKLLS2; NBLA00548; VMLDS2
Summary	The protein encoded by this gene is a member of the protocadherin family. This gene may play a role in regulating planar cell polarity (PCP). Studies in mice suggest that loss of PCP signaling may cause cystic kidney disease, and mutations in this gene have been associated with Van Maldergem Syndrome 2. Alternatively spliced transcript variants have been noted for this gene. [provided by RefSeq, Mar 2014]

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