Human HRPT2 (CDC73) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	CDC73
Locus ID	79577
Kit Components	GA112467G1, HRPT2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA112467G2, HRPT2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA112467G3, HRPT2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_024529
Synonyms	C1orf28; FIHP; HPTJT; HRPT1; HRPT2; HYX
Summary	This gene encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. This protein appears to facilitate the association of 3' mRNA processing factors with actively-transcribed chromatin. Mutations in this gene have been linked to hyperparathyroidism-jaw tumor syndrome, familial isolated hyperparathyroidism, and parathyroid carcinoma. [provided by RefSeq, Jul 2009]

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