Human C2ORF47 (MAIP1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	MAIP1
Locus ID	79568
Kit Components	GA112459G1, C2ORF47 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA112459G2, C2ORF47 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA112459G3, C2ORF47 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_024520, NM_001369399, NR_161377
Synonyms	DKFZp666A212; FLJ22555
Summary	Promotes sorting of SMDT1/EMRE in mitochondria by ensuring its maturation (PubMed:27642048). Interacts with the transit peptide region of SMDT1/EMRE precursor protein in the mitochondrial matrix, leading to protect it against protein degradation by YME1L1, thereby ensuring SMDT1/EMRE maturation by the mitochondrial processing peptidase (PMPCA and PMPCB) (PubMed:27642048).[UniProtKB/Swiss-Prot Function]

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