Human SHARP1 (BHLHE41) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	BHLHE41
Locus ID	79365
Kit Components	GA112432G1, SHARP1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA112432G2, SHARP1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA112432G3, SHARP1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_030762
Synonyms	BHLHB3; DEC2; hDEC2; SHARP1
Summary	This gene encodes a basic helix-loop-helix protein expressed in various tissues. The encoded protein can interact with ARNTL or compete for E-box binding sites in the promoter of PER1 and repress CLOCK/ARNTL's transactivation of PER1. This gene is believed to be involved in the control of circadian rhythm and cell differentiation. Defects in this gene are associated with the short sleep phenotype. [provided by RefSeq, Feb 2014]

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