Human CENPO activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	CENPO
Locus ID	79172
Kit Components	GA112401G1, CENPO gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA112401G2, CENPO gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA112401G3, CENPO gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001199803, NM_001322101, NM_024322, NR_136182, NR_136183, NR_136184
Synonyms	CENP-O; ICEN-36; MCM21R
Summary	This gene encodes a component of the interphase centromere complex. The encoded protein is localized to the centromere throughout the cell cycle and is required for bipolar spindle assembly, chromosome segregation and checkpoint signaling during mitosis. Alternatively spliced transcript variants encoding multiple protein isoforms have been observed for this gene. [provided by RefSeq, Dec 2010]

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