Human Persephin receptor (GFRA4) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	GFRA4
Locus ID	64096
Kit Components	GA111970G1, Persephin receptor gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA111970G2, Persephin receptor gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA111970G3, Persephin receptor gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_022139, NM_145762, NM_145763
Synonyms	GDNF family receptor alpha 4; GFR receptor alpha 4; OTTHUMP00000030106; OTTHUMP00000030107; persephin receptor
Summary	The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for persephin, and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for RET-associated diseases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]

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