Human EPS15R (EPS15L1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	EPS15L1
Locus ID	58513
Kit Components	GA111793G1, EPS15R gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA111793G2, EPS15R gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA111793G3, EPS15R gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001258374, NM_001258375, NM_001258376, NM_021235, NR_047665, NR_047666
Synonyms	EPS15R
Summary	Seems to be a constitutive component of clathrin-coated pits that is required for receptor-mediated endocytosis. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR); internalization of ITGB1 as DAB2-dependent cargo but not TFR seems to require association with DAB2.[UniProtKB/Swiss-Prot Function]

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