Human ARHGAP22 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ARHGAP22
Locus ID	58504
Kit Components	GA111785G1, ARHGAP22 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA111785G2, ARHGAP22 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA111785G3, ARHGAP22 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001256024, NM_001256025, NM_001256026, NM_021226, NR_045675, NM_001347735, NM_001347736, NM_001347737, NM_001347738, NR_144642, NR_144643, NR_144644, NR_144645, NR_144646, NM_001256027
Synonyms	RhoGAP2; RhoGap22
Summary	This gene encodes a member of the GTPase activating protein family which activates a GTPase belonging to the RAS superfamily of small GTP-binding proteins. The encoded protein is insulin-responsive, is dependent on the kinase Akt and requires the Akt-dependent 14-3-3 binding protein which binds sequentially to two serine residues. The result of these interactions is regulation of cell motility. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]

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