Human POLD4 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	POLD4
Locus ID	57804
Kit Components	GA111732G1, POLD4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA111732G2, POLD4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA111732G3, POLD4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001256870, NM_021173, NR_046411, NR_046412, NR_046413
Synonyms	p12; POLDS
Summary	This gene encodes the smallest subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. The encoded protein enhances the activity of DNA polymerase delta and plays a role in fork repair and stabilization through interactions with the DNA helicase Bloom syndrome protein. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012]

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