Human TRIB3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	TRIB3
Locus ID	57761
Kit Components	GA111723G1, TRIB3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA111723G2, TRIB3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA111723G3, TRIB3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001301188, NM_001301190, NM_001301193, NM_001301196, NM_001301201, NM_021158
Synonyms	C20orf97; NIPK; SINK; SKIP3; TRB3
Summary	The protein encoded by this gene is a putative protein kinase that is induced by the transcription factor NF-kappaB. The encoded protein is a negative regulator of NF-kappaB and can also sensitize cells to TNF- and TRAIL-induced apoptosis. In addition, this protein can negatively regulate the cell survival serine-threonine kinase AKT1. Differential promoter usage and alternate splicing result in multiple transcript variants. [provided by RefSeq, Jul 2014]

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