Human TRIB3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	TRIB3
Locus ID	57761
Kit Components	GA111723G1, TRIB3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA111723G2, TRIB3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA111723G3, TRIB3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001301188, NM_001301190, NM_001301193, NM_001301196, NM_001301201, NM_021158
Synonyms	C20orf97; NIPK; SINK; SKIP3; TRB3
Summary	The protein encoded by this gene is a putative protein kinase that is induced by the transcription factor NF-kappaB. The encoded protein is a negative regulator of NF-kappaB and can also sensitize cells to TNF- and TRAIL-induced apoptosis. In addition, this protein can negatively regulate the cell survival serine-threonine kinase AKT1. Differential promoter usage and alternate splicing result in multiple transcript variants. [provided by RefSeq, Jul 2014]

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