Human ZNF537 (TSHZ3) activation kit by CRISPRa
CAT#: GA111636
TSHZ3 CRISPRa kit - CRISPR gene activation of human teashirt zinc finger homeobox 3
CNY 12,255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | TSHZ3 |
Locus ID | 57616 |
Kit Components | GA111636G1, ZNF537 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA111636G2, ZNF537 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA111636G3, ZNF537 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_020856, NR_138034, NR_138035, NR_138036 |
Synonyms | TSH3; ZNF537 |
Summary | This gene encodes a zinc-finger transcription factor that regulates smooth muscle cell differentiation in the developing urinary tract. Consistent with this role, mice in which this gene has been inactivated exhibit abnormal gene expression in urinary tract smooth muscle cell precursors and kidney defects including hydronephrosis. The encoded transcription factor comprises a gene silencing complex that inhibits caspase expression. Reduced expression of this gene and consequent caspase upregulation may be correlated with progression of Alzheimer's disease in human patients. [provided by RefSeq, Jul 2016] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN411499 | TSHZ3 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |