Human WDR48 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	WDR48
Locus ID	57599
Kit Components	GA111623G1, WDR48 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA111623G2, WDR48 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA111623G3, WDR48 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001303402, NM_001303403, NM_020839, NM_001346225, NM_001346226, NM_001346227, NM_001346228, NR_144399, NR_144400, NR_144401
Synonyms	P80; SPG60; UAF1
Summary	The protein encoded by this gene has been shown to interact with ubiquitin specific peptidase 1 (USP1), activating the deubiquitinating activity of USP1 and allowing it to remove the ubiquitin moiety from monoubiquitinated FANCD2. FANCD2 is ubiquitinated in response to DNA damage. [provided by RefSeq, Sep 2016]

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