Human ARHGAP21 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ARHGAP21
Locus ID	57584
Kit Components	GA111610G1, ARHGAP21 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA111610G2, ARHGAP21 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA111610G3, ARHGAP21 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_020824, NM_001367447, NM_001367448, NM_001367453, NM_001367454, NR_160022, NR_160024, NM_001367449, NM_001367450, NM_001367451, NM_001367452, NM_001367455, NR_160021, NR_160023, NR_160025
Synonyms	ARHGAP10
Summary	ARHGAP21 functions preferentially as a GTPase-activating protein (GAP) for CDC42 (MIM 116952) and regulates the ARP2/3 complex (MIM 604221) and F-actin dynamics at the Golgi through control of CDC42 activity (Dubois et al., 2005 [PubMed 15793564]).[supplied by OMIM, Mar 2008]

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