Human HACE1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	HACE1
Locus ID	57531
Kit Components	GA111564G1, HACE1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA111564G2, HACE1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA111564G3, HACE1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_020771, NR_104424, NM_001321080, NM_001321083, NM_001321084, NM_001350554, NM_001350555, NM_001350556, NM_001350557, NM_001350558, NM_001350559, NM_001350560, NR_146787, NR_146788, NR_146789, NR_146790, NR_146791, NR_146792
Synonyms	HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 1
Summary	This gene encodes a HECT domain and ankyrin repeat-containing ubiquitin ligase. The encoded protein is involved in specific tagging of target proteins, leading to their subcellular localization or proteasomal degradation. The protein is a potential tumor suppressor and is involved in the pathophysiology of several tumors, including Wilm's tumor. [provided by RefSeq, Mar 2016]

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