Human CYP20A1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	CYP20A1
Locus ID	57404
Kit Components	GA111481G1, CYP20A1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA111481G2, CYP20A1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA111481G3, CYP20A1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_020674, NM_177538
Synonyms	CYP-M; CYP-M, MGC22229; cytochrome P450 monooxygenase; cytochrome P450, family 20, subfamily A, polypeptide 1; MGC22229
Summary	This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein lacks one amino acid of the conserved heme binding site. It also lacks the conserved I-helix motif AGX(D,E)T, suggesting that its substrate may carry its own oxygen. [provided by RefSeq, Jul 2008]

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