Human SENP7 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SENP7
Locus ID	57337
Kit Components	GA111469G1, SENP7 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA111469G2, SENP7 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA111469G3, SENP7 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001077203, NM_001282801, NM_001282802, NM_001282803, NM_001282804, NM_020654
Synonyms	KIAA1707; MGC157730
Summary	The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1; MIM 601912) is required for many cellular processes. SUMO-specific proteases, such as SENP7, process SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also display isopeptidase activity for deconjugation of SUMO-conjugated substrates (Lima and Reverter, 2008 [PubMed 18799455]).[supplied by OMIM, Jun 2009]

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