Human MDM1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	MDM1
Locus ID	56890
Kit Components	GA111243G1, MDM1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA111243G2, MDM1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA111243G3, MDM1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001205028, NM_001205029, NM_017440, NM_020128, NM_001354969, NM_001354970, NM_001354971, NM_001354972, NM_001354973, NM_001354974, NM_001368282
Synonyms	FLJ95264
Summary	This gene encodes a microtubule-binding nuclear protein that localizes to the centrioles of dividing cells and differentiating multiciliated cells and negatively regulates centriole duplication. The encoded protein is closely associated with the centriole barrel, and resides in the centriole lumen. Naturally-occurring mutations in the orthologous mouse gene are associated with age-related retinal degeneration. [provided by RefSeq, Feb 2019]

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