Human Leukotriene B4 Receptor 2 (LTB4R2) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	LTB4R2
Locus ID	56413
Kit Components	GA111187G1, Leukotriene B4 Receptor 2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA111187G2, Leukotriene B4 Receptor 2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA111187G3, Leukotriene B4 Receptor 2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001164692, NM_001164693, NM_019839
Synonyms	BLT2; BLTR2; JULF2; KPG_004; LTB4-R 2; LTB4-R2; NOP9
Summary	Low-affinity receptor for leukotrienes including leukotriene B4. Mediates chemotaxis of granulocytes and macrophages. The response is mediated via G-proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTB4 > 12-epi-LTB4 > LTB5 > LTB3.[UniProtKB/Swiss-Prot Function]

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