Human LIM domain only 3 (LMO3) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	LMO3
Locus ID	55885
Kit Components	GA111038G1, LIM domain only 3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA111038G2, LIM domain only 3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA111038G3, LIM domain only 3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001001395, NM_001243609, NM_001243610, NM_001243611, NM_001243612, NM_001243613, NM_018640, NR_045012, NR_045013, NR_045014
Synonyms	RBTN3; RBTNL2; Rhom-3; RHOM3
Summary	The protein encoded by this gene belongs to the rhombotin family of cysteine-rich LIM domain oncogenes. This gene is predominantly expressed in the brain. Related family members, LMO1 and LMO2 on chromosome 11, have been reported to be involved in chromosomal translocations in T-cell leukemia. Many alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2011]

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