Human C1orf103 (LRIF1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	LRIF1
Locus ID	55791
Kit Components	GA110973G1, C1orf103 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA110973G2, C1orf103 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA110973G3, C1orf103 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001006945, NM_018372
Synonyms	C1orf103; RIF1
Summary	Together with SMCHD1, involved in chromosome X inactivation in females by promoting the compaction of heterochromatin (PubMed:23542155). Also able to repress the ligand-induced transcriptional activity of retinoic acid receptor alpha (RARA), possibly through direct recruitment of histone deacetylases (PubMed:17455211).[UniProtKB/Swiss-Prot Function]

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